DAAM1-C12ORF10 Fusion FISH Probe
The DAAM1-C12ORF10 Fusion FISH Probe is used to confirm a fusion of the DAAM1 and C12ORF10 genes. The fusion of the DAAM1 and C12ORF10 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DAAM1-C12ORF10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-RERE | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-REOR | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-REGO | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-REGR | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-REAQ | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-ORRE | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-OROR | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-ORGO | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-ORAQ | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-GORE | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-GOOR | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-GOGO | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-GOGR | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-GOAQ | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-GRRE | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-GROR | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-GRGO | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-GRGR | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-GRAQ | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-AQRE | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-AQOR | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-AQGO | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-AQGR | 20 (40 μL) | 200 μL |
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| DAAM1-C12ORF10-20-AQAQ | 20 (40 μL) | 200 μL |
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DAAM1 Gene Summary
Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2012]
Gene Name: Dishevelled Associated Activator Of Morphogenesis 1
Chromosome: CHR14: 59655398 -59836471
Locus: 14q23.1
C12orf10 Gene Summary
The Chromosome 12 Open Reading Frame 10 (C12orf10) gene is located on chr12 :53693469-53700965 at 12q13.13.
Gene Name: Chromosome 12 Open Reading Frame 10
Chromosome: CHR12: 53693469 -53700965
Locus: 12q13.13
Gene Diseases
The DAAM1 C12ORF10 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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