CYTIP-MGAT5 Fusion FISH Probe
The CYTIP-MGAT5 Fusion FISH Probe is used to confirm a fusion of the CYTIP and MGAT5 genes. The fusion of the CYTIP and MGAT5 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CYTIP-MGAT5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-RERE | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-REOR | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-REGO | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-REGR | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-REAQ | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-ORRE | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-OROR | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-ORGO | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-ORAQ | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-GORE | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-GOOR | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-GOGO | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-GOGR | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-GOAQ | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-GRRE | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-GROR | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-GRGO | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-GRGR | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-GRAQ | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-AQRE | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-AQOR | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-AQGO | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-AQGR | 20 (40 μL) | 200 μL |
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| CYTIP-MGAT5-20-AQAQ | 20 (40 μL) | 200 μL |
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MGAT5 Gene Summary
The protein encoded by this gene belongs to the glycosyltransferase family. It catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the activity of this enzyme has been correlated with the progression of invasive malignancies. [provided by RefSeq, Oct 2011]
Gene Name: Mannosyl (alpha-1,6-)-glycoprotein Beta-1,6-N-acetyl-glucosaminyltransferase
Chromosome: CHR2: 135011829 -135206468
Locus: 2q21.2-q21.3
CYTIP Gene Summary
The protein encoded by this gene contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, but does not have any hydrophobic regions. This protein is expressed weakly in resting NK and T cells. The encoded protein modulates the activation of ARF genes by CYTH1. This protein interacts with CYTH1 and SNX27 proteins and may act to sequester CYTH1 protein in the cytoplasm.[provided by RefSeq, Aug 2008]
Gene Name: Cytohesin 1 Interacting Protein
Chromosome: CHR2: 158271130 -158300604
Locus: 2q24.1
Gene Diseases
The CYTIP MGAT5 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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