CXCL14-SUPT16H Fusion FISH Probe
The CXCL14-SUPT16H Fusion FISH Probe is used to confirm a fusion of the CXCL14 and SUPT16H genes. The fusion of the CXCL14 and SUPT16H genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CXCL14-SUPT16H-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-RERE | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-REOR | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-REGO | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-REGR | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-REAQ | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-ORRE | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-OROR | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-ORGO | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-ORAQ | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-GORE | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-GOOR | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-GOGO | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-GOGR | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-GOAQ | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-GRRE | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-GROR | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-GRGO | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-GRGR | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-GRAQ | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-AQRE | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-AQOR | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-AQGO | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-AQGR | 20 (40 μL) | 200 μL |
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| CXCL14-SUPT16H-20-AQAQ | 20 (40 μL) | 200 μL |
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CXCL14 Gene Summary
This antimicrobial gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. [provided by RefSeq, Sep 2014]
Gene Name: C-X-C Motif Chemokine Ligand 14
Chromosome: CHR5: 134906370 -134914969
Locus: 5q31.1
SUPT16H Gene Summary
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. [provided by RefSeq, Feb 2009]
Gene Name: SPT16 Homolog, Facilitates Chromatin Remodeling Subunit
Chromosome: CHR14: 21819630 -21852425
Locus: 14q11.2
Gene Diseases
The CXCL14 SUPT16H Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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