CUL5-OPCML Fusion FISH Probe
The CUL5-OPCML Fusion FISH Probe is used to confirm a fusion of the CUL5 and OPCML genes. The fusion of the CUL5 and OPCML genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CUL5-OPCML-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-RERE | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-REOR | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-REGO | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-REGR | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-REAQ | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-ORRE | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-OROR | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-ORGO | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-ORAQ | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-GORE | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-GOOR | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-GOGO | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-GOGR | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-GOAQ | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-GRRE | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-GROR | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-GRGO | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-GRGR | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-GRAQ | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-AQRE | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-AQOR | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-AQGO | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-AQGR | 20 (40 μL) | 200 μL |
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| CUL5-OPCML-20-AQAQ | 20 (40 μL) | 200 μL |
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OPCML Gene Summary
This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. The encoded preprotein is proteolytically processed to generate the mature protein. This protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Gene Name: Opioid Binding Protein/cell Adhesion Molecule Like
Chromosome: CHR11: 132284874 -133402403
Locus: 11q25
CUL5 Gene Summary
The Cullin 5 (CUL5) gene is located on chr11 :107879407-107978488 at 11q22.3.
Gene Name: Cullin 5
Chromosome: CHR11: 107879407 -107978488
Locus: 11q22.3
Gene Diseases
The CUL5 OPCML Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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