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CTTN-PLEKHA5 Fusion FISH Probe

The CTTN-PLEKHA5 Fusion FISH Probe is used to confirm a fusion of the CTTN and PLEKHA5 genes. The fusion of the CTTN and PLEKHA5 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CTTN-PLEKHA5-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-RERE 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-REOR 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-REGO 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-REGR 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-REAQ 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-ORRE 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-OROR 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-ORGO 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-ORAQ 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-GORE 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-GOOR 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-GOGO 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-GOGR 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-GOAQ 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-GRRE 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-GROR 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-GRGO 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-GRGR 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-GRAQ 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-AQRE 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-AQOR 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-AQGO 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-AQGR 20 (40 μL) 200 μL
CTTN-PLEKHA5-20-AQAQ 20 (40 μL) 200 μL

CTTN Gene Summary

This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010]

Gene Name: Cortactin

Chromosome: CHR11: 70244611 -70282690

Locus: 11q13.3

PLEKHA5 Gene Summary

The Pleckstrin Homology Domain Containing A5 (PLEKHA5) gene is located on chr12 :19282625-19529333 at 12p12.3.

Gene Name: Pleckstrin Homology Domain Containing A5

Chromosome: CHR12: 19282625 -19529333

Locus: 12p12.3

Gene Diseases

The CTTN PLEKHA5 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.