CTPS2-RGN Fusion FISH Probe
The CTPS2-RGN Fusion FISH Probe is used to confirm a fusion of the CTPS2 and RGN genes. The fusion of the CTPS2 and RGN genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CTPS2-RGN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-RERE | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-REOR | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-REGO | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-REGR | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-REAQ | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-ORRE | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-OROR | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-ORGO | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-ORAQ | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-GORE | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-GOOR | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-GOGO | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-GOGR | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-GOAQ | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-GRRE | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-GROR | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-GRGO | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-GRGR | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-GRAQ | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-AQRE | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-AQOR | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-AQGO | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-AQGR | 20 (40 μL) | 200 μL |
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| CTPS2-RGN-20-AQAQ | 20 (40 μL) | 200 μL |
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RGN Gene Summary
The protein encoded by this gene is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Name: Regucalcin
Chromosome: CHRX: 46937774 -46952712
Locus: Xp11.3
CTPS2 Gene Summary
The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Gene Name: CTP Synthase 2
Chromosome: CHRX: 16606121 -16731059
Locus: Xp22.2
Gene Diseases
The CTPS2 RGN Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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