CTNND2-NRBP1 Fusion FISH Probe
The CTNND2-NRBP1 Fusion FISH Probe is used to confirm a fusion of the CTNND2 and NRBP1 genes. The fusion of the CTNND2 and NRBP1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CTNND2-NRBP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-RERE | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-REOR | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-REGO | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-REGR | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-REAQ | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-ORRE | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-OROR | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-ORGO | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-GORE | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-GOOR | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-GOGO | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-GOGR | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-GRRE | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-GROR | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-GRGO | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-GRGR | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-AQRE | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-AQOR | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-AQGO | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-AQGR | 20 (40 μL) | 200 μL |
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| CTNND2-NRBP1-20-AQAQ | 20 (40 μL) | 200 μL |
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CTNND2 Gene Summary
This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
Gene Name: Catenin Delta 2
Chromosome: CHR5: 10971951 -11904110
Locus: 5p15.2
NRBP1 Gene Summary
The Nuclear Receptor Binding Protein 1 (NRBP1) gene is located on chr2 :27651472-27665124 at 2p23.3.
Gene Name: Nuclear Receptor Binding Protein 1
Chromosome: CHR2: 27651472 -27665124
Locus: 2p23.3
Gene Diseases
The CTNND2 NRBP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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