CTNNB1-SLC38A5 Fusion FISH Probe
The CTNNB1-SLC38A5 Fusion FISH Probe is used to confirm a fusion of the CTNNB1 and SLC38A5 genes. The fusion of the CTNNB1 and SLC38A5 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CTNNB1-SLC38A5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-RERE | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-REOR | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-REGO | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-REGR | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-REAQ | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-ORRE | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-OROR | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-ORGO | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-ORAQ | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-GORE | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-GOOR | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-GOGO | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-GOGR | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-GOAQ | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-GRRE | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-GROR | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-GRGO | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-GRGR | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-GRAQ | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-AQRE | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-AQOR | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-AQGO | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-AQGR | 20 (40 μL) | 200 μL |
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| CTNNB1-SLC38A5-20-AQAQ | 20 (40 μL) | 200 μL |
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CTNNB1 Gene Summary
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
Gene Name: Catenin Beta 1
Chromosome: CHR3: 41240941 -41281939
Locus: 3p22.1
SLC38A5 Gene Summary
The protein encoded by this gene is a system N sodium-coupled amino acid transporter. The encoded protein transports glutamine, asparagine, histidine, serine, alanine, and glycine across the cell membrane, but does not transport charged amino acids, imino acids, or N-alkylated amino acids. Alternative splicing results in multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Aug 2013]
Gene Name: Solute Carrier Family 38 Member 5
Chromosome: CHRX: 48316926 -48328644
Locus: Xp11.23
Gene Diseases
The CTNNB1 SLC38A5 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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