CTNNA1-WNT8A Fusion FISH Probe
The CTNNA1-WNT8A Fusion FISH Probe is used to confirm a fusion of the CTNNA1 and WNT8A genes. The fusion of the CTNNA1 and WNT8A genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CTNNA1-WNT8A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-RERE | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-REOR | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-REGO | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-REGR | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-REAQ | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-ORRE | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-OROR | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-ORGO | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-ORAQ | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-GORE | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-GOOR | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-GOGO | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-GOGR | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-GOAQ | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-GRRE | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-GROR | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-GRGO | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-GRGR | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-GRAQ | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-AQRE | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-AQOR | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-AQGO | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-AQGR | 20 (40 μL) | 200 μL |
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| CTNNA1-WNT8A-20-AQAQ | 20 (40 μL) | 200 μL |
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CTNNA1 Gene Summary
This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy. [provided by RefSeq, May 2016]
Gene Name: Catenin Alpha 1
Chromosome: CHR5: 138089106 -138270723
Locus: 5q31.2
WNT8A Gene Summary
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and may be implicated in development of early embryos as well as germ cell tumors. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2014]
Gene Name: Wnt Family Member 8A
Chromosome: CHR5: 137419773 -137427199
Locus: 5q31.2
Gene Diseases
The CTNNA1 WNT8A Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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