CTDSPL-WRN Fusion FISH Probe
The CTDSPL-WRN Fusion FISH Probe is used to confirm a fusion of the CTDSPL and WRN genes. The fusion of the CTDSPL and WRN genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CTDSPL-WRN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-RERE | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-REOR | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-REGO | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-REGR | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-REAQ | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-ORRE | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-OROR | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-ORGO | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-ORAQ | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-GORE | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-GOOR | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-GOGO | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-GOGR | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-GOAQ | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-GRRE | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-GROR | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-GRGO | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-GRGR | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-GRAQ | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-AQRE | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-AQOR | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-AQGO | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-AQGR | 20 (40 μL) | 200 μL |
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| CTDSPL-WRN-20-AQAQ | 20 (40 μL) | 200 μL |
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WRN Gene Summary
This gene encodes a member of the RecQ subfamily of DNA helicase proteins. The encoded nuclear protein is important in the maintenance of genome stability and plays a role in DNA repair, replication, transcription and telomere maintenance. This protein contains a N-terminal 3' to 5' exonuclease domain, an ATP-dependent helicase domain and RQC (RecQ helicase conserved region) domain in its central region, and a C-terminal HRDC (helicase RNase D C-terminal) domain and nuclear localization signal. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by accelerated aging and an elevated risk for certain cancers. [provided by RefSeq, Aug 2017]
Gene Name: Werner Syndrome RecQ Like Helicase
Chromosome: CHR8: 30890777 -31031277
Locus: 8p12
CTDSPL Gene Summary
The CTD Small Phosphatase Like (CTDSPL) gene is located on chr3 :37903668-38025960 at 3p22.2.
Gene Name: CTD Small Phosphatase Like
Chromosome: CHR3: 37903668 -38025960
Locus: 3p22.2
Gene Diseases
The CTDSPL WRN Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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