CTBP2-ADAM12 Fusion FISH Probe
The CTBP2-ADAM12 Fusion FISH Probe is used to confirm a fusion of the CTBP2 and ADAM12 genes. The fusion of the CTBP2 and ADAM12 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CTBP2-ADAM12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-RERE | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-REOR | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-REGO | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-REGR | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-OROR | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-GORE | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-GROR | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| CTBP2-ADAM12-20-AQAQ | 20 (40 μL) | 200 μL |
|
CTBP2 Gene Summary
This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]
Gene Name: C-terminal Binding Protein 2
Chromosome: CHR10: 126676417 -126849624
Locus: 10q26.13
ADAM12 Gene Summary
This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form. [provided by RefSeq, Jan 2014]
Gene Name: ADAM Metallopeptidase Domain 12
Chromosome: CHR10: 127702901 -128077127
Locus: 10q26.2
Gene Diseases
The CTBP2 ADAM12 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|