CSNK2B-CCT5 Fusion FISH Probe
The CSNK2B-CCT5 Fusion FISH Probe is used to confirm a fusion of the CSNK2B and CCT5 genes. The fusion of the CSNK2B and CCT5 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CSNK2B-CCT5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-RERE | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-REOR | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-REGO | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-REGR | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-REAQ | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-ORRE | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-OROR | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-ORGO | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-ORAQ | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-GORE | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-GOOR | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-GOGO | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-GOGR | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-GOAQ | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-GRRE | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-GROR | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-GRGO | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-GRGR | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-GRAQ | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-AQRE | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-AQOR | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-AQGO | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-AQGR | 20 (40 μL) | 200 μL |
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| CSNK2B-CCT5-20-AQAQ | 20 (40 μL) | 200 μL |
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CSNK2B Gene Summary
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Gene Name: Casein Kinase 2 Beta
Chromosome: CHR6_dbb_hap3: 2919235 -2923423
Locus: 6p21.33
CCT5 Gene Summary
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]
Gene Name: Chaperonin Containing TCP1 Subunit 5
Chromosome: CHR5: 10250281 -10266501
Locus: 5p15.2
Gene Diseases
The CSNK2B CCT5 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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