CSNK1E-PHF5A Fusion FISH Probe
The CSNK1E-PHF5A Fusion FISH Probe is used to confirm a fusion of the CSNK1E and PHF5A genes. The fusion of the CSNK1E and PHF5A genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CSNK1E-PHF5A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-RERE | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-REOR | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-REGO | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-REGR | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-REAQ | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-ORRE | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-OROR | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-ORGO | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-ORAQ | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-GORE | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-GOOR | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-GOGO | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-GOGR | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-GOAQ | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-GRRE | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-GROR | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-GRGO | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-GRGR | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-GRAQ | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-AQRE | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-AQOR | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-AQGO | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-AQGR | 20 (40 μL) | 200 μL |
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| CSNK1E-PHF5A-20-AQAQ | 20 (40 μL) | 200 μL |
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CSNK1E Gene Summary
The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]
Gene Name: Casein Kinase 1 Epsilon
Chromosome: CHR22: 38686696 -38714089
Locus: 22q13.1
PHF5A Gene Summary
This gene encodes a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein. This gene has several pseudogenes on different chromosomes. [provided by RefSeq, Jul 2008]
Gene Name: PHD Finger Protein 5A
Chromosome: CHR22: 41855720 -41864708
Locus: 22q13.2
Gene Diseases
The CSNK1E PHF5A Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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