CSNK1E-KDELR3 Fusion FISH Probe
The CSNK1E-KDELR3 Fusion FISH Probe is used to confirm a fusion of the CSNK1E and KDELR3 genes. The fusion of the CSNK1E and KDELR3 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CSNK1E-KDELR3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-RERE | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-REOR | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-REGO | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-REGR | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-REAQ | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-ORRE | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-OROR | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-ORGO | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-ORAQ | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-GORE | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-GOOR | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-GOGO | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-GOGR | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-GOAQ | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-GRRE | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-GROR | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-GRGO | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-GRGR | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-GRAQ | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-AQRE | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-AQOR | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-AQGO | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-AQGR | 20 (40 μL) | 200 μL |
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| CSNK1E-KDELR3-20-AQAQ | 20 (40 μL) | 200 μL |
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CSNK1E Gene Summary
The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]
Gene Name: Casein Kinase 1 Epsilon
Chromosome: CHR22: 38686696 -38714089
Locus: 22q13.1
KDELR3 Gene Summary
This gene encodes a member of the KDEL endoplasmic reticulum protein retention receptor family. Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR3 was the third member of the family to be identified. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: KDEL Endoplasmic Reticulum Protein Retention Receptor 3
Chromosome: CHR22: 38864082 -38879445
Locus: 22q13.1
Gene Diseases
The CSNK1E KDELR3 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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