CSNK1E-DMC1 Fusion FISH Probe
The CSNK1E-DMC1 Fusion FISH Probe is used to confirm a fusion of the CSNK1E and DMC1 genes. The fusion of the CSNK1E and DMC1 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CSNK1E-DMC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-RERE | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-REOR | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-REGO | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-REGR | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-REAQ | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-ORRE | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-OROR | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-ORGO | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-GORE | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-GOOR | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-GOGO | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-GOGR | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-GRRE | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-GROR | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-GRGO | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-GRGR | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-AQRE | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-AQOR | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-AQGO | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-AQGR | 20 (40 μL) | 200 μL |
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| CSNK1E-DMC1-20-AQAQ | 20 (40 μL) | 200 μL |
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CSNK1E Gene Summary
The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]
Gene Name: Casein Kinase 1 Epsilon
Chromosome: CHR22: 38686696 -38714089
Locus: 22q13.1
DMC1 Gene Summary
This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Gene Name: DNA Meiotic Recombinase 1
Chromosome: CHR22: 38914953 -38966189
Locus: 22q13.1
Gene Diseases
The CSNK1E DMC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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