CSK-C15ORF27 Fusion FISH Probe
The CSK-C15ORF27 Fusion FISH Probe is used to confirm a fusion of the CSK and C15ORF27 genes. The fusion of the CSK and C15ORF27 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CSK-C15ORF27-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-RERE | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-REOR | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-REGO | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-REGR | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-OROR | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-GORE | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-GROR | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| CSK-C15ORF27-20-AQAQ | 20 (40 μL) | 200 μL |
|
CSK Gene Summary
The protein encoded by this gene is involved in multiple pathways, including the regulation of Src family kinases. It plays an important role in T-cell activation through its association with the protein encoded by the protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gene. This protein also phosphorylates C-terminal tyrosine residues on multiple substrates, including the protein encoded by the SRC proto-oncogene, non-receptor tyrosine kinase gene. Phosphorylation suppresses the kinase activity of the Src family tyrosine kinases. An intronic polymorphism (rs34933034) in this gene has been found to affect B-cell activation and is associated with systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]
Gene Name: C-terminal Src Kinase
Chromosome: CHR15: 75074424 -75095539
Locus: 15q24.1
Gene Diseases
The CSK C15ORF27 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|