CRY1-HPSE2 Fusion FISH Probe
The CRY1-HPSE2 Fusion FISH Probe is used to confirm a fusion of the CRY1 and HPSE2 genes. The fusion of the CRY1 and HPSE2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CRY1-HPSE2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-RERE | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-REOR | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-REGO | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-REGR | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-REAQ | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-ORRE | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-OROR | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-ORGO | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-GORE | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-GOOR | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-GOGO | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-GOGR | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-GRRE | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-GROR | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-GRGO | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-GRGR | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-AQRE | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-AQOR | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-AQGO | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-AQGR | 20 (40 μL) | 200 μL |
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| CRY1-HPSE2-20-AQAQ | 20 (40 μL) | 200 μL |
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CRY1 Gene Summary
This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014]
Gene Name: Cryptochrome Circadian Regulator 1
Chromosome: CHR12: 107385142 -107487598
Locus: 12q23.3
HPSE2 Gene Summary
This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Name: Heparanase 2 (inactive)
Chromosome: CHR10: 100216833 -100995632
Locus: 10q24.2
Gene Diseases
The CRY1 HPSE2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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