CRTAC1-CCT5 Fusion FISH Probe
The CRTAC1-CCT5 Fusion FISH Probe is used to confirm a fusion of the CRTAC1 and CCT5 genes. The fusion of the CRTAC1 and CCT5 genes has been associated with Uveal Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CRTAC1-CCT5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-RERE | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-REOR | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-REGO | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-REGR | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-REAQ | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-ORRE | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-OROR | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-ORGO | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-ORAQ | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-GORE | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-GOOR | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-GOGO | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-GOGR | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-GOAQ | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-GRRE | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-GROR | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-GRGO | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-GRGR | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-GRAQ | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-AQRE | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-AQOR | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-AQGO | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-AQGR | 20 (40 μL) | 200 μL |
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| CRTAC1-CCT5-20-AQAQ | 20 (40 μL) | 200 μL |
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CCT5 Gene Summary
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]
Gene Name: Chaperonin Containing TCP1 Subunit 5
Chromosome: CHR5: 10250281 -10266501
Locus: 5p15.2
CRTAC1 Gene Summary
This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Gene Name: Cartilage Acidic Protein 1
Chromosome: CHR10: 99624756 -99790585
Locus: 10q24.2
Gene Diseases
The CRTAC1 CCT5 Fusion has been associated with the following diseases:
| Disease Name |
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| Uveal Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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