CRLS1-TRMT6 Fusion FISH Probe
The CRLS1-TRMT6 Fusion FISH Probe is used to confirm a fusion of the CRLS1 and TRMT6 genes. The fusion of the CRLS1 and TRMT6 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CRLS1-TRMT6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-RERE | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-REOR | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-REGO | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-REGR | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-REAQ | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-ORRE | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-OROR | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-ORGO | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-ORAQ | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-GORE | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-GOOR | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-GOGO | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-GOGR | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-GOAQ | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-GRRE | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-GROR | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-GRGO | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-GRGR | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-GRAQ | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-AQRE | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-AQOR | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-AQGO | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-AQGR | 20 (40 μL) | 200 μL |
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| CRLS1-TRMT6-20-AQAQ | 20 (40 μL) | 200 μL |
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TRMT6 Gene Summary
This gene encodes a member of the tRNA methyltransferase 6 protein family. A similar protein in yeast is part of a two component methyltransferase, which is involved in the posttranslational modification that produces the modified nucleoside 1-methyladenosine in tRNAs. Modified 1-methyladenosine influences initiator methionine stability and may be involved in the replication of human immunodeficiency virus type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: TRNA Methyltransferase 6
Chromosome: CHR20: 5918485 -5931173
Locus: 20p12.3
CRLS1 Gene Summary
This gene encodes a member of the CDP-alcohol phosphatidyltransferase class-I family of proteins. The encoded enzyme catalyzes the synthesis of cardiolipin, a phospholipid component of mitochondrial membranes that is critical for mitochondrial function. [provided by RefSeq, Apr 2016]
Gene Name: Cardiolipin Synthase 1
Chromosome: CHR20: 5986738 -6020697
Locus: 20p12.3
Gene Diseases
The CRLS1 TRMT6 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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