CRISPLD2-MPZL2 Fusion FISH Probe
The CRISPLD2-MPZL2 Fusion FISH Probe is used to confirm a fusion of the CRISPLD2 and MPZL2 genes. The fusion of the CRISPLD2 and MPZL2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CRISPLD2-MPZL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-RERE | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-REOR | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-REGO | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-REGR | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-REAQ | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-ORRE | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-OROR | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-ORGO | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-GORE | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-GOOR | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-GOGO | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-GOGR | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-GRRE | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-GROR | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-GRGO | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-GRGR | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-AQRE | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-AQOR | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-AQGO | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-AQGR | 20 (40 μL) | 200 μL |
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| CRISPLD2-MPZL2-20-AQAQ | 20 (40 μL) | 200 μL |
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MPZL2 Gene Summary
Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Myelin Protein Zero Like 2
Chromosome: CHR11: 118124130 -118135251
Locus: 11q23.3
CRISPLD2 Gene Summary
The Cysteine Rich Secretory Protein LCCL Domain Containing 2 (CRISPLD2) gene is located on chr16 :84853586-84943116 at 16q24.1.
Gene Name: Cysteine Rich Secretory Protein LCCL Domain Containing 2
Chromosome: CHR16: 84853586 -84943116
Locus: 16q24.1
Gene Diseases
The CRISPLD2 MPZL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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