CRIP1-AP1G2 Fusion FISH Probe
The CRIP1-AP1G2 Fusion FISH Probe is used to confirm a fusion of the CRIP1 and AP1G2 genes. The fusion of the CRIP1 and AP1G2 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CRIP1-AP1G2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-RERE | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-REOR | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-REGO | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-REGR | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-REAQ | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-ORRE | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-OROR | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-ORGO | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-GORE | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-GOOR | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-GOGO | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-GOGR | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-GRRE | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-GROR | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-GRGO | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-GRGR | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-AQRE | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-AQOR | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-AQGO | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-AQGR | 20 (40 μL) | 200 μL |
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| CRIP1-AP1G2-20-AQAQ | 20 (40 μL) | 200 μL |
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CRIP1 Gene Summary
Cysteine-rich intestinal protein (CRIP) belongs to the LIM/double zinc finger protein family, members of which include cysteine- and glycine-rich protein-1 (CSRP1; MIM 123876), rhombotin-1 (RBTN1; MIM 186921), rhombotin-2 (RBTN2; MIM 180385), and rhombotin-3 (RBTN3; MIM 180386). CRIP may be involved in intestinal zinc transport (Hempe and Cousins, 1991 [PubMed 1946385]).[supplied by OMIM, Mar 2008]
Gene Name: Cysteine Rich Protein 1
Chromosome: CHR14: 105953256 -105955124
Locus: 14q32.33
AP1G2 Gene Summary
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. This protein along with the complex is thought to function at some trafficking step in the complex pathways between the trans-Golgi network and the cell surface. [provided by RefSeq, Aug 2017]
Gene Name: Adaptor Related Protein Complex 1 Gamma 2 Subunit
Chromosome: CHR14: 24028776 -24037279
Locus: 14q11.2
Gene Diseases
The CRIP1 AP1G2 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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