CRIM1-TACR1 Fusion FISH Probe
The CRIM1-TACR1 Fusion FISH Probe is used to confirm a fusion of the CRIM1 and TACR1 genes. The fusion of the CRIM1 and TACR1 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CRIM1-TACR1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-RERE | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-REOR | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-REGO | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-REGR | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-REAQ | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-ORRE | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-OROR | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-ORGO | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-GORE | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-GOOR | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-GOGO | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-GOGR | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-GRRE | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-GROR | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-GRGO | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-GRGR | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-AQRE | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-AQOR | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-AQGO | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-AQGR | 20 (40 μL) | 200 μL |
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| CRIM1-TACR1-20-AQAQ | 20 (40 μL) | 200 μL |
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TACR1 Gene Summary
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq, Sep 2008]
Gene Name: Tachykinin Receptor 1
Chromosome: CHR2: 75273589 -75426645
Locus: 2p12
CRIM1 Gene Summary
This gene encodes a transmembrane protein containing six cysteine-rich repeat domains and an insulin-like growth factor-binding domain. The encoded protein may play a role in tissue development though interactions with members of the transforming growth factor beta family, such as bone morphogenetic proteins. [provided by RefSeq, Nov 2010]
Gene Name: Cysteine Rich Transmembrane BMP Regulator 1
Chromosome: CHR2: 36583369 -36778278
Locus: 2p22.2
Gene Diseases
The CRIM1 TACR1 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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