CREB3L3-PKN3 Fusion FISH Probe
The CREB3L3-PKN3 Fusion FISH Probe is used to confirm a fusion of the CREB3L3 and PKN3 genes. The fusion of the CREB3L3 and PKN3 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CREB3L3-PKN3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-RERE | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-REOR | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-REGO | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-REGR | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-REAQ | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-ORRE | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-OROR | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-ORGO | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-ORAQ | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-GORE | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-GOOR | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-GOGO | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-GOGR | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-GOAQ | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-GRRE | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-GROR | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-GRGO | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-GRGR | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-GRAQ | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-AQRE | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-AQOR | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-AQGO | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-AQGR | 20 (40 μL) | 200 μL |
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| CREB3L3-PKN3-20-AQAQ | 20 (40 μL) | 200 μL |
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PKN3 Gene Summary
The Protein Kinase N3 (PKN3) gene is located on chr9 :131464801-131483199 at 9q34.11.
Gene Name: Protein Kinase N3
Chromosome: CHR9: 131464801 -131483199
Locus: 9q34.11
CREB3L3 Gene Summary
This gene encodes a member of the basic-leucine zipper family and the AMP-dependent transcription factor family. The encoded protein is localized to the endoplasmic reticulum and acts as a transcription factor activated by cyclic AMP stimulation. The encoded protein binds the cyclic AMP response element (CRE) and the box-B element and has been linked to acute inflammatory response, hepatocellular carcinoma, triglyceride metabolism, and hepcidin expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Gene Name: CAMP Responsive Element Binding Protein 3 Like 3
Chromosome: CHR19: 4153628 -4173048
Locus: 19p13.3
Gene Diseases
The CREB3L3 PKN3 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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