CRB1-IGFN1 Fusion FISH Probe
The CRB1-IGFN1 Fusion FISH Probe is used to confirm a fusion of the CRB1 and IGFN1 genes. The fusion of the CRB1 and IGFN1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CRB1-IGFN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-RERE | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-REOR | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-REGO | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-REGR | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-REAQ | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-ORRE | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-OROR | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-ORGO | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-GORE | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-GOOR | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-GOGO | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-GOGR | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-GRRE | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-GROR | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-GRGO | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-GRGR | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-AQRE | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-AQOR | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-AQGO | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-AQGR | 20 (40 μL) | 200 μL |
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| CRB1-IGFN1-20-AQAQ | 20 (40 μL) | 200 μL |
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CRB1 Gene Summary
This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternate splicing results in multiple transcript variants, some protein coding and some non-protein coding.[provided by RefSeq, Apr 2012]
Gene Name: Crumbs 1, Cell Polarity Complex Component
Chromosome: CHR1: 197237333 -197447585
Locus: 1q31.3
IGFN1 Gene Summary
The Immunoglobulin-like And Fibronectin Type III Domain Containing 1 (IGFN1) gene is located on chr1 :201159952-201198080 at 1q32.1.
Gene Name: Immunoglobulin-like And Fibronectin Type III Domain Containing 1
Chromosome: CHR1: 201159952 -201198080
Locus: 1q32.1
Gene Diseases
The CRB1 IGFN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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