CPT2-SCP2 Fusion FISH Probe
The CPT2-SCP2 Fusion FISH Probe is used to confirm a fusion of the CPT2 and SCP2 genes. The fusion of the CPT2 and SCP2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CPT2-SCP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-RERE | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-REOR | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-REGO | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-REGR | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-REAQ | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-ORRE | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-OROR | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-ORGO | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-GORE | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-GOOR | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-GOGO | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-GOGR | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-GRRE | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-GROR | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-GRGO | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-GRGR | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-AQRE | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-AQOR | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-AQGO | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-AQGR | 20 (40 μL) | 200 μL |
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| CPT2-SCP2-20-AQAQ | 20 (40 μL) | 200 μL |
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CPT2 Gene Summary
The protein encoded by this gene is a nuclear protein which is transported to the mitochondrial inner membrane. Together with carnitine palmitoyltransferase I, the encoded protein oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders. [provided by RefSeq, Jul 2008]
Gene Name: Carnitine Palmitoyltransferase 2
Chromosome: CHR1: 53662100 -53679869
Locus: 1p32.3
SCP2 Gene Summary
This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.[provided by RefSeq, Aug 2010]
Gene Name: Sterol Carrier Protein 2
Chromosome: CHR1: 53392900 -53517289
Locus: 1p32.3
Gene Diseases
The CPT2 SCP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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