CPT1B-SEC14L3 Fusion FISH Probe
The CPT1B-SEC14L3 Fusion FISH Probe is used to confirm a fusion of the CPT1B and SEC14L3 genes. The fusion of the CPT1B and SEC14L3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CPT1B-SEC14L3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-RERE | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-REOR | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-REGO | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-REGR | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-REAQ | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-ORRE | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-OROR | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-ORGO | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-ORAQ | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-GORE | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-GOOR | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-GOGO | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-GOGR | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-GOAQ | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-GRRE | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-GROR | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-GRGO | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-GRGR | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-GRAQ | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-AQRE | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-AQOR | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-AQGO | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-AQGR | 20 (40 μL) | 200 μL |
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| CPT1B-SEC14L3-20-AQAQ | 20 (40 μL) | 200 μL |
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CPT1B Gene Summary
The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009]
Gene Name: Carnitine Palmitoyltransferase 1B
Chromosome: CHR22: 51007289 -51017096
Locus: 22q13.33
SEC14L3 Gene Summary
The protein encoded by this gene is highly similar to the protein encoded by the Saccharomyces cerevisiae SEC14 gene. The SEC14 protein is a phophatidylinositol transfer protein that is essential for biogenesis of Golgi-derived transport vesicles, and thus is required for the export of yeast secretory proteins from the Golgi complex. The specific function of this protein has not yet been determined. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Name: SEC14 Like Lipid Binding 3
Chromosome: CHR22: 30855215 -30868034
Locus: 22q12.2
Gene Diseases
The CPT1B SEC14L3 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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