CPT1A-MAPK8IP3 Fusion FISH Probe
The CPT1A-MAPK8IP3 Fusion FISH Probe is used to confirm a fusion of the CPT1A and MAPK8IP3 genes. The fusion of the CPT1A and MAPK8IP3 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CPT1A-MAPK8IP3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-RERE | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-REOR | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-REGO | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-REGR | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-OROR | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-GORE | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-GROR | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| CPT1A-MAPK8IP3-20-AQAQ | 20 (40 μL) | 200 μL |
|
CPT1A Gene Summary
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Carnitine Palmitoyltransferase 1A
Chromosome: CHR11: 68522087 -68609399
Locus: 11q13.3
MAPK8IP3 Gene Summary
The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Mitogen-activated Protein Kinase 8 Interacting Protein 3
Chromosome: CHR16: 1756220 -1820318
Locus: 16p13.3
Gene Diseases
The CPT1A MAPK8IP3 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|