CPT1A-ADAM2 Fusion FISH Probe
The CPT1A-ADAM2 Fusion FISH Probe is used to confirm a fusion of the CPT1A and ADAM2 genes. The fusion of the CPT1A and ADAM2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CPT1A-ADAM2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| CPT1A-ADAM2-20-AQAQ | 20 (40 μL) | 200 μL |
|
CPT1A Gene Summary
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Carnitine Palmitoyltransferase 1A
Chromosome: CHR11: 68522087 -68609399
Locus: 11q13.3
ADAM2 Gene Summary
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded protein is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Gene Name: ADAM Metallopeptidase Domain 2
Chromosome: CHR8: 39601254 -39695779
Locus: 8p11.22
Gene Diseases
The CPT1A ADAM2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|