CPSF6-OSBPL8 Fusion FISH Probe
The CPSF6-OSBPL8 Fusion FISH Probe is used to confirm a fusion of the CPSF6 and OSBPL8 genes. The fusion of the CPSF6 and OSBPL8 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CPSF6-OSBPL8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-RERE | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-REOR | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-REGO | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-REGR | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-REAQ | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-ORRE | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-OROR | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-ORGO | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-ORAQ | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-GORE | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-GOOR | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-GOGO | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-GOGR | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-GOAQ | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-GRRE | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-GROR | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-GRGO | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-GRGR | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-GRAQ | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-AQRE | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-AQOR | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-AQGO | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-AQGR | 20 (40 μL) | 200 μL |
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| CPSF6-OSBPL8-20-AQAQ | 20 (40 μL) | 200 μL |
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CPSF6 Gene Summary
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. [provided by RefSeq, Jul 2008]
Gene Name: Cleavage And Polyadenylation Specific Factor 6
Chromosome: CHR12: 69633316 -69668138
Locus: 12q15
OSBPL8 Gene Summary
This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Name: Oxysterol Binding Protein Like 8
Chromosome: CHR12: 76745577 -76953589
Locus: 12q21.2
Gene Diseases
The CPSF6 OSBPL8 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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