CPSF6-CPM Fusion FISH Probe
The CPSF6-CPM Fusion FISH Probe is used to confirm a fusion of the CPSF6 and CPM genes. The fusion of the CPSF6 and CPM genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CPSF6-CPM-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-RERE | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-REOR | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-REGO | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-REGR | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-REAQ | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-ORRE | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-OROR | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-ORGO | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-ORAQ | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-GORE | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-GOOR | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-GOGO | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-GOGR | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-GOAQ | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-GRRE | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-GROR | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-GRGO | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-GRGR | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-GRAQ | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-AQRE | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-AQOR | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-AQGO | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-AQGR | 20 (40 μL) | 200 μL |
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| CPSF6-CPM-20-AQAQ | 20 (40 μL) | 200 μL |
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CPM Gene Summary
The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Carboxypeptidase M
Chromosome: CHR12: 69244955 -69357020
Locus: 12q15
CPSF6 Gene Summary
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. [provided by RefSeq, Jul 2008]
Gene Name: Cleavage And Polyadenylation Specific Factor 6
Chromosome: CHR12: 69633316 -69668138
Locus: 12q15
Gene Diseases
The CPSF6 CPM Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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