CPSF6-COL9A1 Fusion FISH Probe
The CPSF6-COL9A1 Fusion FISH Probe is used to confirm a fusion of the CPSF6 and COL9A1 genes. The fusion of the CPSF6 and COL9A1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CPSF6-COL9A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-RERE | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-REOR | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-REGO | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-REGR | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-REAQ | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-ORRE | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-OROR | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-ORGO | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-GORE | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-GOOR | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-GOGO | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-GOGR | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-GRRE | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-GROR | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-GRGO | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-GRGR | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-AQRE | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-AQOR | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-AQGO | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-AQGR | 20 (40 μL) | 200 μL |
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| CPSF6-COL9A1-20-AQAQ | 20 (40 μL) | 200 μL |
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COL9A1 Gene Summary
This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Collagen Type IX Alpha 1 Chain
Chromosome: CHR6: 70925742 -71012786
Locus: 6q13
CPSF6 Gene Summary
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. [provided by RefSeq, Jul 2008]
Gene Name: Cleavage And Polyadenylation Specific Factor 6
Chromosome: CHR12: 69633316 -69668138
Locus: 12q15
Gene Diseases
The CPSF6 COL9A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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