CPSF1-AHNAK Fusion FISH Probe
The CPSF1-AHNAK Fusion FISH Probe is used to confirm a fusion of the CPSF1 and AHNAK genes. The fusion of the CPSF1 and AHNAK genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CPSF1-AHNAK-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-RERE | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-REOR | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-REGO | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-REGR | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-REAQ | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-ORRE | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-OROR | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-ORGO | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-ORAQ | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-GORE | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-GOOR | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-GOGO | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-GOGR | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-GOAQ | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-GRRE | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-GROR | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-GRGO | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-GRGR | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-GRAQ | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-AQRE | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-AQOR | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-AQGO | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-AQGR | 20 (40 μL) | 200 μL |
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| CPSF1-AHNAK-20-AQAQ | 20 (40 μL) | 200 μL |
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CPSF1 Gene Summary
Cleavage and polyadenylation specificity factor (CPSF) is a multisubunit complex that plays a central role in 3-prime processing of pre-mRNAs. CPSF recognizes the AAUAAA signal in the pre-mRNA and interacts with other proteins to facilitate both RNA cleavage and poly(A) synthesis. CPSF1 is the largest subunit of the CPSF complex (Murthy and Manley, 1995 [PubMed 7590244]).[supplied by OMIM, Mar 2008]
Gene Name: Cleavage And Polyadenylation Specific Factor 1
Chromosome: CHR8: 145618445 -145634733
Locus: 8q24.3
AHNAK Gene Summary
The protein encoded by this gene is a large (700 kDa) structural scaffold protein consisting of a central domain with 128 aa repeats. The encoded protein may play a role in such diverse processes as blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis. A much shorter variant encoding a 17 kDa isoform exists for this gene, and the shorter isoform initiates a feedback loop that regulates alternative splicing of this gene. [provided by RefSeq, Oct 2016]
Gene Name: AHNAK Nucleoprotein
Chromosome: CHR11: 62201015 -62314332
Locus: 11q12.3
Gene Diseases
The CPSF1 AHNAK Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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