CPS1-PLEKHM3 Fusion FISH Probe
The CPS1-PLEKHM3 Fusion FISH Probe is used to confirm a fusion of the CPS1 and PLEKHM3 genes. The fusion of the CPS1 and PLEKHM3 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CPS1-PLEKHM3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-RERE | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-REOR | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-REGO | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-REGR | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-OROR | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-GORE | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-GROR | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| CPS1-PLEKHM3-20-AQAQ | 20 (40 μL) | 200 μL |
|
CPS1 Gene Summary
The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.[provided by RefSeq, May 2010]
Gene Name: Carbamoyl-phosphate Synthase 1
Chromosome: CHR2: 211342405 -211543831
Locus: 2q34
PLEKHM3 Gene Summary
The Pleckstrin Homology Domain Containing M3 (PLEKHM3) gene is located on chr2 :208686011-208890284 at 2q33.3.
Gene Name: Pleckstrin Homology Domain Containing M3
Chromosome: CHR2: 208686011 -208890284
Locus: 2q33.3
Gene Diseases
The CPS1 PLEKHM3 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|