CPNE8-PRMT8 Fusion FISH Probe
The CPNE8-PRMT8 Fusion FISH Probe is used to confirm a fusion of the CPNE8 and PRMT8 genes. The fusion of the CPNE8 and PRMT8 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CPNE8-PRMT8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-RERE | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-REOR | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-REGO | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-REGR | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-REAQ | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-ORRE | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-OROR | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-ORGO | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-ORAQ | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-GORE | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-GOOR | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-GOGO | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-GOGR | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-GOAQ | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-GRRE | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-GROR | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-GRGO | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-GRGR | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-GRAQ | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-AQRE | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-AQOR | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-AQGO | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-AQGR | 20 (40 μL) | 200 μL |
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| CPNE8-PRMT8-20-AQAQ | 20 (40 μL) | 200 μL |
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PRMT8 Gene Summary
Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation (Lee et al., 2005 [PubMed 16051612]).[supplied by OMIM, Mar 2008]
Gene Name: Protein Arginine Methyltransferase 8
Chromosome: CHR12: 3600424 -3703138
Locus: 12p13.32
CPNE8 Gene Summary
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. [provided by RefSeq, Jul 2008]
Gene Name: Copine 8
Chromosome: CHR12: 39046001 -39299420
Locus: 12q12
Gene Diseases
The CPNE8 PRMT8 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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