CPNE8-MGST1 Fusion FISH Probe
The CPNE8-MGST1 Fusion FISH Probe is used to confirm a fusion of the CPNE8 and MGST1 genes. The fusion of the CPNE8 and MGST1 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CPNE8-MGST1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-RERE | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-REOR | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-REGO | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-REGR | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-REAQ | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-ORRE | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-OROR | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-ORGO | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-GORE | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-GOOR | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-GOGO | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-GOGR | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-GRRE | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-GROR | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-GRGO | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-GRGR | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-AQRE | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-AQOR | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-AQGO | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-AQGR | 20 (40 μL) | 200 μL |
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| CPNE8-MGST1-20-AQAQ | 20 (40 μL) | 200 μL |
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MGST1 Gene Summary
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene. [provided by RefSeq, May 2012]
Gene Name: Microsomal Glutathione S-transferase 1
Chromosome: CHR12: 16500075 -16517344
Locus: 12p12.3
CPNE8 Gene Summary
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. [provided by RefSeq, Jul 2008]
Gene Name: Copine 8
Chromosome: CHR12: 39046001 -39299420
Locus: 12q12
Gene Diseases
The CPNE8 MGST1 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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