CPNE1-NDUFV1 Fusion FISH Probe
The CPNE1-NDUFV1 Fusion FISH Probe is used to confirm a fusion of the CPNE1 and NDUFV1 genes. The fusion of the CPNE1 and NDUFV1 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CPNE1-NDUFV1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-RERE | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-REOR | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-REGO | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-REGR | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-REAQ | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-ORRE | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-OROR | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-ORGO | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-GORE | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-GOOR | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-GOGO | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-GOGR | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-GRRE | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-GROR | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-GRGO | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-GRGR | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-AQRE | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-AQOR | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-AQGO | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-AQGR | 20 (40 μL) | 200 μL |
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| CPNE1-NDUFV1-20-AQAQ | 20 (40 μL) | 200 μL |
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NDUFV1 Gene Summary
The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]
Gene Name: NADH:ubiquinone Oxidoreductase Core Subunit V1
Chromosome: CHR11: 67374322 -67380012
Locus: 11q13.2
CPNE1 Gene Summary
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the encoded protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking. This gene and the gene for RNA binding motif protein 12 overlap at map location 20q11.21. Alternate splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Aug 2008]
Gene Name: Copine 1
Chromosome: CHR20: 34213952 -34252878
Locus: 20q11.22
Gene Diseases
The CPNE1 NDUFV1 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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