CPNE1-DMD Fusion FISH Probe
The CPNE1-DMD Fusion FISH Probe is used to confirm a fusion of the CPNE1 and DMD genes. The fusion of the CPNE1 and DMD genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CPNE1-DMD-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-RERE | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-REOR | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-REGO | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-REGR | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-REAQ | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-ORRE | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-OROR | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-ORGO | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-ORAQ | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-GORE | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-GOOR | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-GOGO | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-GOGR | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-GOAQ | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-GRRE | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-GROR | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-GRGO | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-GRGR | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-GRAQ | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-AQRE | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-AQOR | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-AQGO | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-AQGR | 20 (40 μL) | 200 μL |
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| CPNE1-DMD-20-AQAQ | 20 (40 μL) | 200 μL |
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DMD Gene Summary
This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]
Gene Name: Dystrophin
Chromosome: CHRX: 31137344 -33357726
Locus: Xp21.2-p21.1
CPNE1 Gene Summary
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the encoded protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking. This gene and the gene for RNA binding motif protein 12 overlap at map location 20q11.21. Alternate splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Aug 2008]
Gene Name: Copine 1
Chromosome: CHR20: 34213952 -34252878
Locus: 20q11.22
Gene Diseases
The CPNE1 DMD Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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