CPD-AATF Fusion FISH Probe
The CPD-AATF Fusion FISH Probe is used to confirm a fusion of the CPD and AATF genes. The fusion of the CPD and AATF genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CPD-AATF-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-RERE | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-REOR | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-REGO | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-REGR | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-REAQ | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-ORRE | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-OROR | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-ORGO | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-ORAQ | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-GORE | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-GOOR | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-GOGO | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-GOGR | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-GOAQ | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-GRRE | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-GROR | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-GRGO | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-GRGR | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-GRAQ | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-AQRE | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-AQOR | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-AQGO | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-AQGR | 20 (40 μL) | 200 μL |
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| CPD-AATF-20-AQAQ | 20 (40 μL) | 200 μL |
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CPD Gene Summary
The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Carboxypeptidase D
Chromosome: CHR17: 28705941 -28796675
Locus: 17q11.2
AATF Gene Summary
The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008]
Gene Name: Apoptosis Antagonizing Transcription Factor
Chromosome: CHR17: 35306174 -35414171
Locus: 17q12
Gene Diseases
The CPD AATF Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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