CPB1-DDX21 Fusion FISH Probe
The CPB1-DDX21 Fusion FISH Probe is used to confirm a fusion of the CPB1 and DDX21 genes. The fusion of the CPB1 and DDX21 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CPB1-DDX21-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-RERE | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-REOR | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-REGO | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-REGR | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-REAQ | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-ORRE | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-OROR | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-ORGO | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-ORAQ | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-GORE | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-GOOR | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-GOGO | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-GOGR | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-GOAQ | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-GRRE | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-GROR | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-GRGO | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-GRGR | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-GRAQ | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-AQRE | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-AQOR | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-AQGO | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-AQGR | 20 (40 μL) | 200 μL |
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| CPB1-DDX21-20-AQAQ | 20 (40 μL) | 200 μL |
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CPB1 Gene Summary
Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. [provided by RefSeq, Jul 2008]
Gene Name: Carboxypeptidase B1
Chromosome: CHR3: 148545587 -148577972
Locus: 3q24
DDX21 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. [provided by RefSeq, Jul 2008]
Gene Name: DExD-box Helicase 21
Chromosome: CHR10: 70715891 -70744279
Locus: 10q22.1
Gene Diseases
The CPB1 DDX21 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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