CPB1-ATP5G3 Fusion FISH Probe
The CPB1-ATP5G3 Fusion FISH Probe is used to confirm a fusion of the CPB1 and ATP5G3 genes. The fusion of the CPB1 and ATP5G3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CPB1-ATP5G3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-RERE | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-REOR | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-REGO | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-REGR | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-REAQ | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-ORRE | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-OROR | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-ORGO | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-ORAQ | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-GORE | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-GOOR | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-GOGO | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-GOGR | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-GOAQ | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-GRRE | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-GROR | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-GRGO | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-GRGR | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-GRAQ | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-AQRE | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-AQOR | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-AQGO | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-AQGR | 20 (40 μL) | 200 μL |
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| CPB1-ATP5G3-20-AQAQ | 20 (40 μL) | 200 μL |
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ATP5G3 Gene Summary
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding different proteins have been identified. [provided by RefSeq, Jun 2010]
Gene Name: ATP Synthase, H+ Transporting, Mitochondrial Fo Complex Subunit C3 (subunit 9)
Chromosome: CHR2: 176040985 -176046490
Locus: 2q31.1
CPB1 Gene Summary
Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. [provided by RefSeq, Jul 2008]
Gene Name: Carboxypeptidase B1
Chromosome: CHR3: 148545587 -148577972
Locus: 3q24
Gene Diseases
The CPB1 ATP5G3 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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