CPA1-SCYL1 Fusion FISH Probe
The CPA1-SCYL1 Fusion FISH Probe is used to confirm a fusion of the CPA1 and SCYL1 genes. The fusion of the CPA1 and SCYL1 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CPA1-SCYL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-RERE | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-REOR | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-REGO | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-REGR | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-REAQ | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-ORRE | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-OROR | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-ORGO | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-GORE | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-GOOR | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-GOGO | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-GOGR | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-GRRE | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-GROR | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-GRGO | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-GRGR | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-AQRE | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-AQOR | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-AQGO | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-AQGR | 20 (40 μL) | 200 μL |
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| CPA1-SCYL1-20-AQAQ | 20 (40 μL) | 200 μL |
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CPA1 Gene Summary
This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer. [provided by RefSeq, Jan 2015]
Gene Name: Carboxypeptidase A1
Chromosome: CHR7: 130020289 -130027949
Locus: 7q32.2
SCYL1 Gene Summary
This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: SCY1 Like Pseudokinase 1
Chromosome: CHR11: 65292547 -65306182
Locus: 11q13.1
Gene Diseases
The CPA1 SCYL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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