COX7C-PLEKHA5 Fusion FISH Probe
The COX7C-PLEKHA5 Fusion FISH Probe is used to confirm a fusion of the COX7C and PLEKHA5 genes. The fusion of the COX7C and PLEKHA5 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| COX7C-PLEKHA5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-RERE | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-REOR | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-REGO | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-REGR | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-REAQ | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-ORRE | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-OROR | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-ORGO | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-ORAQ | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-GORE | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-GOOR | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-GOGO | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-GOGR | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-GOAQ | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-GRRE | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-GROR | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-GRGO | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-GRGR | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-GRAQ | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-AQRE | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-AQOR | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-AQGO | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-AQGR | 20 (40 μL) | 200 μL |
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| COX7C-PLEKHA5-20-AQAQ | 20 (40 μL) | 200 μL |
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COX7C Gene Summary
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIc, which shares 87% and 85% amino acid sequence identity with mouse and bovine COX VIIc, respectively, and is found in all tissues. A pseudogene COX7CP1 has been found on chromosome 13. [provided by RefSeq, Jul 2008]
Gene Name: Cytochrome C Oxidase Subunit 7C
Chromosome: CHR5: 85913783 -85916583
Locus: 5q14.3
PLEKHA5 Gene Summary
The Pleckstrin Homology Domain Containing A5 (PLEKHA5) gene is located on chr12 :19282625-19529333 at 12p12.3.
Gene Name: Pleckstrin Homology Domain Containing A5
Chromosome: CHR12: 19282625 -19529333
Locus: 12p12.3
Gene Diseases
The COX7C PLEKHA5 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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