COX6C-RGS22 Fusion FISH Probe
The COX6C-RGS22 Fusion FISH Probe is used to confirm a fusion of the COX6C and RGS22 genes. The fusion of the COX6C and RGS22 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| COX6C-RGS22-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-RERE | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-REOR | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-REGO | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-REGR | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-REAQ | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-ORRE | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-OROR | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-ORGO | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-ORAQ | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-GORE | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-GOOR | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-GOGO | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-GOGR | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-GOAQ | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-GRRE | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-GROR | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-GRGO | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-GRGR | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-GRAQ | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-AQRE | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-AQOR | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-AQGO | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-AQGR | 20 (40 μL) | 200 μL |
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| COX6C-RGS22-20-AQAQ | 20 (40 μL) | 200 μL |
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COX6C Gene Summary
Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12. [provided by RefSeq, Jul 2010]
Gene Name: Cytochrome C Oxidase Subunit 6C
Chromosome: CHR8: 100890222 -100906242
Locus: 8q22.2
RGS22 Gene Summary
The Regulator Of G Protein Signaling 22 (RGS22) gene is located on chr8 :100973275-101118344 at 8q22.2.
Gene Name: Regulator Of G Protein Signaling 22
Chromosome: CHR8: 100973275 -101118344
Locus: 8q22.2
Gene Diseases
The COX6C RGS22 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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