COX6C-EIF2AK2 Fusion FISH Probe
The COX6C-EIF2AK2 Fusion FISH Probe is used to confirm a fusion of the COX6C and EIF2AK2 genes. The fusion of the COX6C and EIF2AK2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| COX6C-EIF2AK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| COX6C-EIF2AK2-20-AQAQ | 20 (40 μL) | 200 μL |
|
COX6C Gene Summary
Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12. [provided by RefSeq, Jul 2010]
Gene Name: Cytochrome C Oxidase Subunit 6C
Chromosome: CHR8: 100890222 -100906242
Locus: 8q22.2
EIF2AK2 Gene Summary
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2
Chromosome: CHR2: 37333698 -37384190
Locus: 2p22.2
Gene Diseases
The COX6C EIF2AK2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|