CORO2A-C9ORF3 Fusion FISH Probe
The CORO2A-C9ORF3 Fusion FISH Probe is used to confirm a fusion of the CORO2A and C9ORF3 genes. The fusion of the CORO2A and C9ORF3 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CORO2A-C9ORF3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-RERE | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-REOR | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-REGO | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-REGR | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-REAQ | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-ORRE | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-OROR | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-ORGO | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-ORAQ | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-GORE | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-GOOR | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-GOGO | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-GOGR | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-GOAQ | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-GRRE | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-GROR | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-GRGO | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-GRGR | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-GRAQ | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-AQRE | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-AQOR | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-AQGO | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-AQGR | 20 (40 μL) | 200 μL |
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| CORO2A-C9ORF3-20-AQAQ | 20 (40 μL) | 200 μL |
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CORO2A Gene Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
Gene Name: Coronin 2A
Chromosome: CHR9: 100883256 -100954956
Locus: 9q22.33
C9orf3 Gene Summary
This gene encodes a member of the M1 zinc aminopeptidase family. The encoded protein is a zinc-dependent metallopeptidase that catalyzes the removal of an amino acid from the amino terminus of a protein or peptide. This protein may play a role in the generation of angiotensin IV. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010]
Gene Name: Chromosome 9 Open Reading Frame 3
Chromosome: CHR9: 97488950 -97849500
Locus: 9q22.32
Gene Diseases
The CORO2A C9ORF3 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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