COQ4-DNM1 Fusion FISH Probe
The COQ4-DNM1 Fusion FISH Probe is used to confirm a fusion of the COQ4 and DNM1 genes. The fusion of the COQ4 and DNM1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| COQ4-DNM1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| COQ4-DNM1-20-AQAQ | 20 (40 μL) | 200 μL |
|
DNM1 Gene Summary
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: Dynamin 1
Chromosome: CHR9: 130965662 -131017527
Locus: 9q34.11
COQ4 Gene Summary
This gene encodes a component of the coenzyme Q biosynthesis pathway. Coenzyme Q, an essential component of the electron transport chain, shuttles electrons between complexes I or II to complex III of the mitochondrial transport chain. This protein appears to play a structural role in stabilizing a complex that contains most of the coenzyme Q biosynthesis enzymes. Mutations in this gene are associated with mitochondrial disorders linked to coenzyme Q deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Gene Name: Coenzyme Q4
Chromosome: CHR9: 131084790 -131096351
Locus: 9q34.11
Gene Diseases
The COQ4 DNM1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|