COPZ1-GNPTAB Fusion FISH Probe
The COPZ1-GNPTAB Fusion FISH Probe is used to confirm a fusion of the COPZ1 and GNPTAB genes. The fusion of the COPZ1 and GNPTAB genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| COPZ1-GNPTAB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-RERE | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-REOR | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-REGO | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-REGR | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-REAQ | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-ORRE | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-OROR | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-ORGO | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-ORAQ | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-GORE | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-GOOR | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-GOGO | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-GOGR | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-GOAQ | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-GRRE | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-GROR | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-GRGO | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-GRGR | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-GRAQ | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-AQRE | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-AQOR | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-AQGO | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-AQGR | 20 (40 μL) | 200 μL |
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| COPZ1-GNPTAB-20-AQAQ | 20 (40 μL) | 200 μL |
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COPZ1 Gene Summary
This gene encodes a subunit of the cytoplasmic coatamer protein complex, which is involved in autophagy and intracellular protein trafficking. The coatomer protein complex is comprised of seven subunits and functions as the coat protein of coat protein complex (COP)I-vesicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Gene Name: Coatomer Protein Complex Subunit Zeta 1
Chromosome: CHR12: 54718910 -54745633
Locus: 12q13.13
GNPTAB Gene Summary
This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.[provided by RefSeq, May 2010]
Gene Name: N-acetylglucosamine-1-phosphate Transferase Alpha And Beta Subunits
Chromosome: CHR12: 102139274 -102224645
Locus: 12q23.2
Gene Diseases
The COPZ1 GNPTAB Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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