COPS2-CTTN Fusion FISH Probe
The COPS2-CTTN Fusion FISH Probe is used to confirm a fusion of the COPS2 and CTTN genes. The fusion of the COPS2 and CTTN genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| COPS2-CTTN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-RERE | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-REOR | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-REGO | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-REGR | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-REAQ | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-ORRE | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-OROR | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-ORGO | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-ORAQ | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-GORE | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-GOOR | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-GOGO | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-GOGR | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-GOAQ | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-GRRE | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-GROR | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-GRGO | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-GRGR | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-GRAQ | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-AQRE | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-AQOR | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-AQGO | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-AQGR | 20 (40 μL) | 200 μL |
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| COPS2-CTTN-20-AQAQ | 20 (40 μL) | 200 μL |
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CTTN Gene Summary
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010]
Gene Name: Cortactin
Chromosome: CHR11: 70244611 -70282690
Locus: 11q13.3
COPS2 Gene Summary
The COP9 Signalosome Subunit 2 (COPS2) gene is located on chr15 :49417470-49447854 at 15q21.1.
Gene Name: COP9 Signalosome Subunit 2
Chromosome: CHR15: 49417470 -49447854
Locus: 15q21.1
Gene Diseases
The COPS2 CTTN Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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