COPE-TMED1 Fusion FISH Probe
The COPE-TMED1 Fusion FISH Probe is used to confirm a fusion of the COPE and TMED1 genes. The fusion of the COPE and TMED1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| COPE-TMED1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-RERE | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-REOR | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-REGO | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-REGR | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-REAQ | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-ORRE | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-OROR | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-ORGO | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-ORAQ | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-GORE | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-GOOR | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-GOGO | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-GOGR | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-GOAQ | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-GRRE | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-GROR | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-GRGO | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-GRGR | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-GRAQ | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-AQRE | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-AQOR | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-AQGO | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-AQGR | 20 (40 μL) | 200 μL |
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| COPE-TMED1-20-AQAQ | 20 (40 μL) | 200 μL |
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TMED1 Gene Summary
This gene belongs to the TMED (transmembrane emp24 domain-containing) protein family, which is involved in the vesicular trafficking of proteins. The protein encoded by this gene was identified by its interaction with interleukin 1 receptor-like 1 (IL1RL1) and may play a role in innate immunity. This protein lacks any similarity to other interleukin 1 ligands. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Gene Name: Transmembrane P24 Trafficking Protein 1
Chromosome: CHR19: 10943113 -10946983
Locus: 19p13.2
COPE Gene Summary
The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Coatomer Protein Complex Subunit Epsilon
Chromosome: CHR19: 19010322 -19030199
Locus: 19p13.11
Gene Diseases
The COPE TMED1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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