COL4A5-XRCC4 Fusion FISH Probe
The COL4A5-XRCC4 Fusion FISH Probe is used to confirm a fusion of the COL4A5 and XRCC4 genes. The fusion of the COL4A5 and XRCC4 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| COL4A5-XRCC4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-RERE | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-REOR | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-REGO | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-REGR | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-REAQ | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-ORRE | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-OROR | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-ORGO | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-ORAQ | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-GORE | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-GOOR | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-GOGO | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-GOGR | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-GOAQ | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-GRRE | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-GROR | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-GRGO | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-GRGR | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-GRAQ | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-AQRE | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-AQOR | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-AQGO | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-AQGR | 20 (40 μL) | 200 μL |
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| COL4A5-XRCC4-20-AQAQ | 20 (40 μL) | 200 μL |
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COL4A5 Gene Summary
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]
Gene Name: Collagen Type IV Alpha 5 Chain
Chromosome: CHRX: 107683153 -107940775
Locus: Xq22.3
XRCC4 Gene Summary
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants. [provided by RefSeq, Dec 2015]
Gene Name: X-ray Repair Cross Complementing 4
Chromosome: CHR5: 82373316 -82649579
Locus: 5q14.2
Gene Diseases
The COL4A5 XRCC4 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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